Retinal ReSculpt™ Overnight Treatment Refill

Transform your skin with Retinal ReSculpt Overnight Treatment. This next-gen night serum dramatically lifts and reduces skin sagging in just 2 weeks.

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It’s been formulated with encapsulated retinal—one of the most efficacious forms of vitamin A in an exclusive delivery system. It offers enhanced stability and targeted delivery deep within skin’s surface, allowing 2.5x better effectiveness compared to free retinal, while still being gentle on skin. This advanced formula has been enriched with complementary ingredients that amplify retinal’s benefits: Kangaroo paw flower and olive leaf extracts help improve saggy appearance, smooth wrinkles and support resilience, while oat lipids and alpha glucan help replenish ceramides, increase moisture and soothe the skin.​

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  • Visibly lifts the neck & jowl sagging in 2 weeks​
  • Smooths wrinkles, including deep ones in 2 weeks​
  • Reduces crepey skin in 2 weeks​
  • Increases skin elasticity in 4 weeks​
  • Ensures deep hydration overnight​
  • Leaves the skin supple, soft and moisturised​
  • 1 refill reduces packaging material by 85% and fits into your Retinal ReSculpt Overnight Treatment bottle (sold separately)

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Recommended as a "midlife must-have" by India Knight from the Sunday Times Style

SKU: 15011
Murad

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A person holding a Retinol ReSculpt Overnight Treatment

Pharmaceutical-inspired encapsulation for 2.5x better efficacy (vs. free retinal)

Details

All retinoids must convert to retinoic acid before they can elicit change. Retinal converts once and retinol converts twice. Retinal works faster than retinol because it takes less time to convert into an active and start working in the skin, reducing visible signs of ageing. Our high-tech night serum features encapsulated retinal - one of the most efficacious forms of vitamin A in a delivery system that’s adapted from technology used in pharmaceutical applications. With enhanced stability and targeted delivery deep within skin’s surface, this overnight treatment can create transformative results in just 2 weeks, with care you expect from a doctor.​

Which skin type is it good for?
  • Balanced·
  • Oily·
  • Dry·
  • Combination·
  • With visible ageing signs like loss of elasticity, skin sagging and wrinkles
Video

With 4,000+ types of retinoids, here’s how to find the right one for you

This Harvard-trained Dermatologist breaks down the difference between retinOL and retinAL—and why knowing the difference is critical to addressing your unique ageing skin concerns

Results

Unretouched Real Results

In 2 weeks:

  • Neck & Jowl area is visibly lifted, with reduced sagging*
  • Deep-set wrinkles and crepey skin are smoothened*

 

In 4 weeks:

  • Skin elasticity is visibly increased*

*Results based on an 8-week clinical study with 34 participants

Ingredients

Expert, science-backed ingredients and patented technologies

HOW-TO

To Use: PM

A tube od Renewing Cleansing Cream
Step 1

Massage Renewing Cleansing Cream over dampened face, neck and closed eyes. Rinse and pat dry.

Step 2

Apply a thin layer of Retinal ReSculpt Overnight Treatment to face and neck.

Step 3

Massage Retinal ReSculpt Overnight Cream evenly over face and neck. If you experience any sensitivity, switch to a non-retinol night cream. Follow with a sunscreen during the day.

What’s your retin-type? Use Retinol Serum for mild-to-moderate ageing and Retinal ReSculpt to amp up results for advanced ageing

Get the Facts

How Diet And Weight Loss Affects Skin

From Weight Loss to Skin Tightening: Understanding the Full Picture Learn More

Can retinal counteract signs of ageing on stressed skin?

What you need to know about this derm-approved powerhouse Learn More

Overall rating: 4.7716703 / 5 from 473 reviews.

AI Generated Review Summary

Customers have praised the Retinal ReSculpt Overnight Treatment Refill for its ability to visibly lift and reduce sagging skin, smooth wrinkles, and improve skin texture. The product is formulated with encapsulated retinal and complementary ingredients to enhance its effectiveness and gentleness on the skin.

Summary topics

  • Visible Results (14%): Customers appreciated the incredible and amazing results they achieved with this product, with many expressing their satisfaction and happiness.
  • Fresh Scent (9%): It was highlighted by customers that the product has a great fresh scent that is not overpowering.
  • Skin Feel (15%): Customers keep praising how smooth and soft their skin feels after using the product, describing it as smooth, soft, and amazing.

Review topics: ["feels","packaging","skin","issues","results","looks","improvement","smells","wrinkles","texture","face","price","spots","irritation","formula","lines","consistency","bottle","fragrance","difference","pores","reduction","weight","serum","glow","residue","benefits","cream","appearance","redness"].

Review highlights

  • "My skin looks radiant, my skin looks firm, improved dark spots and my skin has a more even skin tone, love this product." — Lorena O.
  • "My skin felt great and I noticed a visible difference after just a week of use." — Andrew D.
  • "My fine lines also appear smoother, and my skin looks more radiant when I wake up." — Anonymous

Reviews

Great neck serum!

"I was able to test this serum for 4 weeks thanks to Gloss Angeles. The serum feels luxurious upon application and absorbs quickly. I found after nightly use that my neck appeared more firm and the texture was less crepey. My tech neck wrinkles and jowls also slightly diminished. I’m excited about seeing my results with using it even longer."

— Andrea T. (5/5)

Great Serum for skincare lovers

"This serum is very nice, I have used 2 pumps every night and have seen improvements in my skin texture in a few weeks. It has a very faint fragrance, feels nice on the skin and penetrates quickly. I found my skin to look smoother and improved texture, would definitely give this a try. I did not have any irritation with the retinal. I received this product to test through Gloss Angeles for my honest review"

— Marcela R. (5/5)

Great Product!

"This is one of the first products that I have tried that actually works. I have noticeably less wrinkles and sagging skin under my chin. I was gifted this product in exchange for my honest review from Gloss Angeles. I will continue to purchase this in the future. It is a little pricy but it has lasted a long time (been using it for 4 weeks and bottle still feels full) but worth the price since it actually works."

— Lauren (5/5)

Excellent neck cream

"I have enjoyed using this neck cream even though I would've never thought to purchase it. I did tan a lot when I was younger and I do feel like this gave my neck and delicate a smoother and softer appearance when I used it & I have already recommended this to friends! I think if you’re looking for a neck serum that is going to provide results with consistent use, this is the one! In the future, I would repurchase this. I received this product as a part of Gloss Angeles confidential, thank you Gloss Angeles!"

— Disa W. (5/5)

Thick and Smooth Serum

"I was gifted this product from Gloss Angeles & liked applying the serum to my neck as it felt thick yet went on smooth on my neck and chest. Tried this for four weeks but didn’t notice much of a visible difference on my neck or chest but I do like how smooth my skin feels. Will continue to try this product for another four weeks."

— Lineth H. (3/5)

Good Product Overall

"I received Murad’s Retinal ReSculpt Overnight Treatment to test as part of Gloss Angeles’ seeding program. After using it consistently, I’d give it 4/5 stars. My neck looks noticeably smoother and healthier overall, and I was especially pleased that I experienced no irritation or sensitivity. I have two visible horizontal lines on my neck—one deeper crease and one finer line. While I haven’t noticed much change in the deeper line, the finer one does appear softer and less noticeable. I wouldn’t call the results dramatic, but I’ve definitely seen an improvement in my skin’s overall texture and appearance. A solid, gentle retinal treatment that I'd recommend if you need to target and improve the neck area!"

— Paige R. (4/5)

Very subtle differences

"I got to try this product thanks to Gloss Angeles. I'm not sure if I saw a huge transformation, but I did see a subtle one. I've tried other neck creams: Skin Science V Line Jaw Defining Serum, Drmtlgy Advanced Neck Cream, Nectifim Advanced Neck Firming Cream, and StriVectin TL Advanced Tightening Neck Cream Plus. I have to say -- this is a rare instance where I have seen subtle differences, and I usually have low expectations of neck creams. The only other neck product that comes close is the Skin Science V Line Jaw Defining Serum. It might also be because this is the first time I've tried a neck cream w/retinal in it. I had zero irritation, which is nice for my sensitive skin. I plan to finish the bottle. I'm not sure, at this price point, if the difference was dramatic enough for me to keep using it. I might just use my retinal eye product and bring it down to my neck as that's more budget-friendly. I guess the best thing is to wait and see if, once I finish the bottle, if my neck doesn't look as good with other retinal products I have. If you have the means, this is worth a shot."

— Jeane W. (4/5)

Excellent

"I”m new to using the murad products, but honestly after 2 weeks I can see a massive improvement in my skin tone and skin texture from using these products It really does work."

— Mary B. (5/5)

Good cream

"So far so good. No irritation, skin is feeling good in the morning. Maybe too early to tell as only been using 1-2 weeks. No problems will continue using daily"

— Donna G. (5/5)

Excellent product

"Excellent product from well researched Murad, Retinal instead of retinal which is better, good consistency with no heavy residue. I feel it’s helping with my dry mature skin."

— Ann T. (5/5)

Q&A

Hi do I use the retinal resculpt overnight treatment under moisturiser like a serum? Is it for every eve or just once or twice a week? Thanks
Hello! Thank you for your question, we hope you’re well. Yes, this product is designed to be used as a serum. Apply a thin, even layer to clean skin. Allow the product to absorb for at least 2 minutes before applying a cream or oil on top. If your skin is still adjusting to this product, we recommend starting with 1–2 uses per week. For sensitive skin, you may wish to apply a buffer before using the Retinal ReSculpt™ Overnight Treatment. A buffer can be a lightweight oil or hydrating serum, and it should be thinner in texture than the Retinal ReSculpt™ Overnight Treatment. To use a buffer: Apply the buffer to clean, dry skin. Allow it to absorb for at least 2 minutes. Then apply your Retinal ReSculpt™ Overnight Treatment. If your skin tolerates this advanced retinal serum well, you may increase usage to 2–3 times per week. Even if your skin is more tolerant, you can still use a buffer if you experience dryness or sensitivity. Finally, please remember to apply SPF during the day when using retinal products. We hope this helps!
Hi, Can I use the Murad rapid collagen infusion followed by the Murad retinal resculpted overnight treatment every evening? Thx
Great question, you can absolutely use both ( this is an exception since we do not generally layer our step two serums) but the best way to use them is to use the Retinal FIRST and follow with Rapid Collagen Infusion for best results. Or using Rapid Collagen Infusion ion the day time and keeping your Retinal for night.
Hi there Please could you let me know the strength of the retinal in this product? I’m currently using 0.1% so hoping for the same or greater. Thanks so much
At Murad we do not disclose our percentages in our high performance formulas as these are considered proprietary. Dr Murad creates formulas based on performance and results rather than percentages, and never relies on a single star ingredient but a complex of ingredients that enhance results. Percentages become more important in prescription strength formulations where patients are gradually introduced to higher strengths because of the potential for irritation. In the case of Retinal Resculpt Overnight Treatment the results are driven by the unique delivery system and the combination of other actives that accelerate the action of the ingredients and deliver faster results without irritation.

Frequently Asked Questions

Retinal Resculpt Overnight Treatment is a next-gen retinal serum suitable for both beginners and advanced retinoids users. It has been formulated with unique encapsulated retinal to deliver 2.5x more efficacy, while remaining gentle on skin. It visibly lifts neck and jowl sagging and smooths deep-set wrinkles in just 2 weeks, improving overall skin elasticity in 4 weeks.

Apply a thin layer of Retinal ReSculpt Overnight Treatment to face and neck after your cleanser and finish with a moisturiser. For enhanced results, finish with Retinal Resculpt Overnight Cream.

Apply Retinal Overnight Treatment to your face and neck after cleansing, before your evening moisturiser. We recommend using Renewing Cleansing Cream beforehand and Retinal Resculpt Overnight Cream to complete your routine.

This high-tech serum features pharmaceutical-inspired encapsulated retinal, to deliver the most efficacious form of vitamin A deep within the skin's surface, while remaining gentle on skin. Paired with Kangaroo Flower, to help improve sagging skin and wrinkles, and Olive, Oat and Alpha Glucan, to boost moisture and counteract the traditional vitamin A drawbacks like dryness and irritation, this serum gives the skin a lifted and sculpted look.

Yes, Retinal ReSculpt Overnight Treatment contains fragrance (parfum).

It's best for people concerned with neck and jowl sagging, deep-set wrinkles, loss of elasticity, and crepey skin.

Retinal usage is not recommended during pregnancy and breastfeeding. For those who may be prone to sensitivity, it's generally best to introduce retinal slowly. Using it just a few nights per week, on non-consecutive evenings, or applying it alongside a moisturiser can help support skin comfort as tolerance builds.

Retinal is formulated for balanced, oily, combination and dry skin types, but can be suitable for sensitive skin. Murad’s retinal formulas are designed with skin health and barrier support in mind. Encapsulated retinal is paired with calming and moisturising ingredients that help replenish ceramides, support the skin barrier, and reduce the likelihood of irritation. This allows retinal to deliver visible results while remaining comfortable for a wider range of skin types.

For those who may be prone to sensitivity, it’s generally best to introduce retinal slowly. Using it just a few nights per week, on non-consecutive evenings, or applying it alongside a moisturiser can help support skin comfort as tolerance builds.

Retinal ReSculpt Overnight Treatment uses encapsulated retinal in a pharmaceutical-inspired delivery system that delivers potent vitamin A deep within the skin's surface, making it 2.5 times more effective than free retinal. The formula works overnight to promote surface cell turnover, boost collagen production, and improve elasticity. Complementary ingredients like Kangaroo Paw Flower and Olive Leaf Extracts help lift sagging skin and smooth wrinkles, while Oat Lipids replenish moisture.

While Retinal ReSculpt Overnight Treatment is formulated with encapsulated retinal and soothing ingredients for enhanced gentleness, those with sensitive or redness-prone skin should start slowly with 2-3 times per week and gradually increase frequency as tolerance builds.