Retinal ReSculpt™ Overnight Treatment Refill

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Transform your skin with Retinal ReSculpt Overnight Treatment. This next-gen night serum dramatically lifts and reduces skin sagging in just 2 weeks.

It’s been formulated with encapsulated retinal—one of the most efficacious forms of vitamin A in an exclusive delivery system. It offers enhanced stability and targeted delivery deep within skin’s surface, allowing 2.5x better effectiveness compared to free retinal, while still being gentle on skin. This advanced formula has been enriched with complementary ingredients that amplify retinal’s benefits: Kangaroo paw flower and olive leaf extracts help improve saggy appearance, smooth wrinkles and support resilience, while oat lipids and alpha glucan help replenish ceramides, increase moisture and soothe the skin.​

  • Visibly lifts the neck & jowl sagging in 2 weeks​
  • Smooths wrinkles, including deep ones in 2 weeks​
  • Reduces crepey skin in 2 weeks​
  • Increases skin elasticity in 4 weeks​
  • Ensures deep hydration overnight​
  • Leaves the skin supple, soft and moisturised​
  • 1 refill reduces packaging material by 85% and fits into your Retinal ReSculpt Overnight Treatment bottle (sold separately)

Recommended as a "midlife must-have" by India Knight from the Sunday Times Style

SKU: 15011
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A person holding a Retinol ReSculpt Overnight Treatment

Pharmaceutical-inspired encapsulation for 2.5x better efficacy (vs. free retinal)

Details

All retinoids must convert to retinoic acid before they can elicit change. Retinal converts once and retinol converts twice. Retinal works faster than retinol because it takes less time to convert into an active and start working in the skin, reducing visible signs of ageing. Our high-tech night serum features encapsulated retinal - one of the most efficacious forms of vitamin A in a delivery system that’s adapted from technology used in pharmaceutical applications. With enhanced stability and targeted delivery deep within skin’s surface, this overnight treatment can create transformative results in just 2 weeks, with care you expect from a doctor.​

Which skin type is it good for?
  • Balanced·
  • Oily·
  • Dry·
  • Combination·
  • With visible ageing signs like loss of elasticity, skin sagging and wrinkles
Video

With 4,000+ types of retinoids, here’s how to find the right one for you

This Harvard-trained Dermatologist breaks down the difference between retinOL and retinAL—and why knowing the difference is critical to addressing your unique ageing skin concerns

Results

Unretouched Real Results

In 2 weeks:

  • Neck & Jowl area is visibly lifted, with reduced sagging*
  • Deep-set wrinkles and crepey skin are smoothened*

 

In 4 weeks:

  • Skin elasticity is visibly increased*

*Results based on an 8-week clinical study with 34 participants

Ingredients

Expert, science-backed ingredients and patented technologies

HOW-TO

To Use: PM

  • A tube od Renewing Cleansing Cream
    Step 1

    Massage Renewing Cleansing Cream over dampened face, neck and closed eyes. Rinse and pat dry.

  • Step 2

    Apply a thin layer of Retinal ReSculpt Overnight Treatment to face and neck.

  • Step 3

    Massage Retinal ReSculpt Overnight Cream evenly over face and neck. If you experience any sensitivity, switch to a non-retinol night cream. Follow with a sunscreen during the day.

What’s your retin-type? Use Retinol Serum for mild-to-moderate ageing and Retinal ReSculpt to amp up results for advanced ageing

Get the Facts

  • How Diet And Weight Loss Affects Skin

    From Weight Loss to Skin Tightening: Understanding the Full Picture Learn More
  • Can retinal counteract signs of ageing on stressed skin?

    What you need to know about this derm-approved powerhouse Learn More

Overall rating: 4.772429 / 5 from 457 reviews.

AI Generated Review Summary

Customers have praised the Retinal ReSculpt Overnight Treatment Refill for its ability to visibly lift and reduce sagging skin, smooth wrinkles, and improve skin texture. The product is formulated with encapsulated retinal and complementary ingredients to enhance its effectiveness and gentleness on the skin.

Summary topics

  • Visible Results (14%): Customers appreciated the incredible and amazing results they achieved with this product, with many expressing their satisfaction and happiness.
  • Fresh Scent (9%): It was highlighted by customers that the product has a great fresh scent that is not overpowering.
  • Skin Feel (15%): Customers keep praising how smooth and soft their skin feels after using the product, describing it as smooth, soft, and amazing.

Review topics: ["fragrance","absorbs","irritation","issues","results","improvement","wrinkles","smells","weight","feels","benefits","price","texture","value","skin","works","packaging","spots","looks","lines","bottle","face","formula","use","consistency","pores","reduction","difference","glow","appearance"].

Review highlights

  • "My skin looks radiant, my skin looks firm, improved dark spots and my skin has a more even skin tone, love this product."Lorena O.
  • "My skin felt great and I noticed a visible difference after just a week of use."Andrew D.
  • "My fine lines also appear smoother, and my skin looks more radiant when I wake up."Anonymous

Reviews

Noticeable improvements in 2-3 weeks

"Noticeable improvements in 2-3 weeks of use!"

Kane B. (5/5)

What a difference this makes!

"I have been using Retinal ReSculpt Overnight treatment for about two months and my skin hasn't glowed like this in decades!! My lines are slowly diminishing (they were quite deep) and my skin feels like it's elasticity and firming is returning. Highly recommend! And, love how this is refillable so I don't need to use a new glass bottle every time. Well done, Murad!!"

Claudia S. (5/5)

It actually works!

"I’ve spent so much on different creams and treatments that claim to work, but this actually does! Perimenopause has not been kind to my neck and I’ve noticed a huge difference in the firmness and texture of the skin under my chin and down my neck after about 3 weeks of using it. Very impressed so far."

Louise M. (5/5)

Murad resurgence

"Fantastic serum, have used it for about a year now, and my skin looks really smooth and lifted. Will definitely keep on using even though I think it is a bit overpriced"

Pat C. (5/5)

Excellent product

"Does exactly what it says, can't recommend highly enough"

Georgia C. (5/5)

Glenis

"I love it 😻 I love your product"

Glenis P. (5/5)

THIS OVERNIGHT TREATMENT DOES REALLY WORK

"I AM DEFINITELY NOTICING A DIFFERENCE USING THIS SERUM. TO BE HONEST, I CAN'T REALLY EXPLAIN IT, BUT MY FACE DOES LOOK A LOT CLEARER AND A BIT LESS WRINKLED AROUND MY MOUTH. I HAVE PUT THIS ON SUBSCRIPTION BECAUSE I NEVER WANT TO BE OUT OF IT."

Dee L. (5/5)

Luxury Experience!

"The encapsulated delivery system has been a game changer for me. I have very sensitive skin and could not tolerate retinol serums by other competitors. Then I tried the Murad ReSculpt products and LOVED them. No more burning, stinging skin as soon as the product goes on. Great job improving my crepey skin texture."

Heather (5/5)

Excellent product

"I ‘ve loved this product I’ve been using for short time my skin looks really nice I’ll buy it again"

Altagracia H. (5/5)

Great product

"The retinol resculpt really works. I haven't used it long but I have faith with regular use I will see my face change. Murad makes great products."

Kassandra K. (5/5)

Q&A

Hi do I use the retinal resculpt overnight treatment under moisturiser like a serum? Is it for every eve or just once or twice a week? Thanks
Hello! Thank you for your question, we hope you’re well. Yes, this product is designed to be used as a serum. Apply a thin, even layer to clean skin. Allow the product to absorb for at least 2 minutes before applying a cream or oil on top. If your skin is still adjusting to this product, we recommend starting with 1–2 uses per week. For sensitive skin, you may wish to apply a buffer before using the Retinal ReSculpt™ Overnight Treatment. A buffer can be a lightweight oil or hydrating serum, and it should be thinner in texture than the Retinal ReSculpt™ Overnight Treatment. To use a buffer: Apply the buffer to clean, dry skin. Allow it to absorb for at least 2 minutes. Then apply your Retinal ReSculpt™ Overnight Treatment. If your skin tolerates this advanced retinal serum well, you may increase usage to 2–3 times per week. Even if your skin is more tolerant, you can still use a buffer if you experience dryness or sensitivity. Finally, please remember to apply SPF during the day when using retinal products. We hope this helps!
Hi, Can I use the Murad rapid collagen infusion followed by the Murad retinal resculpted overnight treatment every evening? Thx
Great question, you can absolutely use both ( this is an exception since we do not generally layer our step two serums) but the best way to use them is to use the Retinal FIRST and follow with Rapid Collagen Infusion for best results. Or using Rapid Collagen Infusion ion the day time and keeping your Retinal for night.
Hi there Please could you let me know the strength of the retinal in this product? I’m currently using 0.1% so hoping for the same or greater. Thanks so much
At Murad we do not disclose our percentages in our high performance formulas as these are considered proprietary. Dr Murad creates formulas based on performance and results rather than percentages, and never relies on a single star ingredient but a complex of ingredients that enhance results. Percentages become more important in prescription strength formulations where patients are gradually introduced to higher strengths because of the potential for irritation. In the case of Retinal Resculpt Overnight Treatment the results are driven by the unique delivery system and the combination of other actives that accelerate the action of the ingredients and deliver faster results without irritation.

Frequently Asked Questions

    Retinal Resculpt Overnight Treatment is a next-gen retinal serum suitable for both beginners and advanced retinoids users. It has been formulated with unique encapsulated retinal to deliver 2.5x more efficacy, while remaining gentle on skin. It visibly lifts neck and jowl sagging and smooths deep-set wrinkles in just 2 weeks, improving overall skin elasticity in 4 weeks.

    Apply a thin layer of Retinal ReSculpt Overnight Treatment to face and neck after your cleanser and finish with a moisturiser. For enhanced results, finish with Retinal Resculpt Overnight Cream.

    Apply Retinal Overnight Treatment to your face and neck after cleansing, before your evening moisturiser. We recommend using Renewing Cleansing Cream beforehand and Retinal Resculpt Overnight Cream to complete your routine.

    This high-tech serum features pharmaceutical-inspired encapsulated retinal, to deliver the most efficacious form of vitamin A deep within the skin's surface, while remaining gentle on skin. Paired with Kangaroo Flower, to help improve sagging skin and wrinkles, and Olive, Oat and Alpha Glucan, to boost moisture and counteract the traditional vitamin A drawbacks like dryness and irritation, this serum gives the skin a lifted and sculpted look.

    Yes, Retinal ReSculpt Overnight Treatment contains fragrance (parfum).

    It's best for people concerned with neck and jowl sagging, deep-set wrinkles, loss of elasticity, and crepey skin.

    Retinal usage is not recommended during pregnancy and breastfeeding. For those who may be prone to sensitivity, it's generally best to introduce retinal slowly. Using it just a few nights per week, on non-consecutive evenings, or applying it alongside a moisturiser can help support skin comfort as tolerance builds.

    Retinal is formulated for balanced, oily, combination and dry skin types, but can be suitable for sensitive skin. Murad’s retinal formulas are designed with skin health and barrier support in mind. Encapsulated retinal is paired with calming and moisturising ingredients that help replenish ceramides, support the skin barrier, and reduce the likelihood of irritation. This allows retinal to deliver visible results while remaining comfortable for a wider range of skin types.

    For those who may be prone to sensitivity, it’s generally best to introduce retinal slowly. Using it just a few nights per week, on non-consecutive evenings, or applying it alongside a moisturiser can help support skin comfort as tolerance builds.

    Retinal ReSculpt Overnight Treatment uses encapsulated retinal in a pharmaceutical-inspired delivery system that delivers potent vitamin A deep within the skin's surface, making it 2.5 times more effective than free retinal. The formula works overnight to promote surface cell turnover, boost collagen production, and improve elasticity. Complementary ingredients like Kangaroo Paw Flower and Olive Leaf Extracts help lift sagging skin and smooth wrinkles, while Oat Lipids replenish moisture.

    While Retinal ReSculpt Overnight Treatment is formulated with encapsulated retinal and soothing ingredients for enhanced gentleness, those with sensitive or redness-prone skin should start slowly with 2-3 times per week and gradually increase frequency as tolerance builds.