Biome-Balancing Clear & Prevent Blemish Treatment Serum

Size
  • 30ML
Like balanced gut health, but for skin.

A breakthrough serum that helps clear all types of blemishes, starting in just 3 days - while supporting skin's unique microbiome.

This treatment features pioneering Biome-Balancing Technology syncing with your skin's unique microbiome to clear blemishes, prevent future breakouts, and promote a healthy, balanced complexion. Powered by Glutamic Acid, it encourages skin’s own microbiome to produce proactive amino acids to support healthy-looking skin. Further enriched with salicylic acid to decongest clogged pores and mandelic acid to smooth and even the skin.

Non-comedogenic, non-drying, non-irritating, layers well under makeup, no pilling or flaking, gentle enough for daily use.

  • Helps clear the skin in just 3 days*
  • Reduces active breakouts, improving skin health and clarity†
  • 92% agreed it hadn't caused unwanted side effects like irritation, peeling, flaking, nor redness.

 

*Consumer testing on 26 subjects in a 4-week study

†Expert grading of photos on 26 subjects in a 4-week study

SKU: 81128
Murad

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Clearer skin starts in just 3 days*

Details

Getting skin clear is all about tackling blemishes. Keeping it clear is all about having a balanced microbiome. You can have both with Murad's latest innovation. This breakthrough serum merges trusted blemish-clearing ingredients like salicylic acid with the ultimate biome-balancing technology to provide a healthier, more balanced microbiome that’s naturally more resistant to recurring blemishes. Result? smoother, clearer skin for the long run.

*Consumer testing on 26 subjects in a 4-week study

What Skin Type is it good for:
  • Balanced ·
  • Oliy·
  • Combination
Results

Untouched real results

  • Clearer skin starts in just 3 days*
  • Reduces active breakouts, improving skin health and clarity†

 

92% agree: no unwanted side effects†:

 

  • peeling 
  • flaking 
  • redness 
  • irritation


*Consumer testing on 26 subjects in a 4-week study

†Expert grading of photos on 26 subjects in a 4-week study

Ingredients

Expert, science-backed ingredients and patented technologies

HOW-TO

To Use: AM and PM

Get the Facts

  • Big zit, now what?

    How to shrink that breakout-fast Learn More
  • Skin freaking out?

    Why hormonal imbalance might be to blame Learn More
CLINICAL NOTE

Why stop at clear skin? Our new Blemish Serum not only treats and prevents breakouts, but also “feeds” good bacteria that empowers your microbiome to thrive—for balanced, healthier-looking skin

Overall rating: 4.888889 / 5 from 36 reviews.

AI Generated Review Summary

This serum helps clear blemishes and supports skin's microbiome, with many users reporting healthier skin in just a few days. It is non-comedogenic, non-drying, and gentle enough for daily use.

Summary topics

  • Breakout Reduction: 20%
  • Skin Feel: 43%
  • Skin Clarity: 48%

Review topics: ["results","feels","skin","smells","looks","breakouts","acne","works","pores","redness","reduction","use","difference","serum","change","treatment"].

Review highlights

  • "With consistent use, skin feels calmer, clearer, and less prone to flare-ups."Gabriele M.
  • "I really love that my skin not only looked healthier but felt healthier."Amaris H.
  • "Since starting the serum, the biggest change I have noticed is that my breakouts have become more manageable."Kathryn

Reviews

Reduced inflammation and acne size!

"Absolutely love this product! It was great addition to my routine once I realized I had a damaged skin barrier. Chin acne improved significantly after a few days of use!"

Whitney (5/5)

best product i’ve ever used

"i swear i refer to this as my magic serum. i suffer from horrible cystic acne and folliculitis and bizarre pimple-like bumps on my chest, back, neck, scalp, and bottom. I’ve tried almost every product on the market that is advertised to solve this kind of skin problem. The only product that ever has worked for me is this one - it’s incredible. If i skip one day of use, i’ll immediately see the bumps reappearing. I go through one bottle in two weeks. I need a larger size option!!"

Danielle (5/5)

Biome-Balancing Clear & Prevent Acne Treatment Serum

"It helps me to not have any breakouts."

Arlene R. (5/5)

Biome balancing gel

"I love this product. I alternate it with the deep relief acne treatment in step 2 of my face wash routine. The acne products work great to maintain clear skin and are the baseline facial treatment that I use regularly."

Maura B. (5/5)

Good

"It is a good product I have seen the difference it makes to my skin. But I am still not sure if it is the right serum for my skin type."

Ngoni M. (5/5)

Amazing

"Thank you so much for this great product. I hope it gets rid of all my whiteheads!"

Neil G. (5/5)

like it!

"Obvious reduction of the redness and breakouts"

Brooke G. (5/5)

the best for acne

"I stopped using the contraceptive and pimples appeared on my cheek. No product was helping me, until I tested this one. It was exactly what I needed: it improved acne without sensitizing my skin too much"

Maria M. (5/5)

El mejor tratamiento para el acne

"Este tratamiento le ayudo mucho ami hija ella tenía brotes en toda la cara grandes y rojos y le ayudo a disminuir rotundamente la rojes gracias"

Norma A. (5/5)

Must have

"I have recently struggled with hormonal acne and have just come across this product and love it. I have pretty sensitive skin and I love that it’s light weight and none drying. It’s really helped balance my skin and help keep it clear."

Cait (5/5)

Q&A

What % of mandalic and salicylic acid does this contain?
Hello Thank you for your question! All Murad products go through safety testing and procedures with FDA and EU guidelines. We don't include the percentages of ingredients on any of our products. Thus being a complex it is not possible to give the exact percentage since it is a formula combination of ingredients. It is worth noting that Dr Murad as a pharmacist and a dermatologist prefers to use complexes and combine with antioxidants and anti inflammatories to give exceptional clinical results within 14 days. He also holds over 19 dermatology related patents, so he really is an expert in this field. However, please note that this product is suitable to AM and PM use. For any further product advice or questions please don't hesitate to reach out to our Customer Care Team on info@murad.co.uk. Thank you.
How is this different from the outsmart blemish treatment? I use the outsmart blemish treatment as a preventative measure on areas where I tend to have mild spots. I used the rapid relief spot treatment when I have a specific spot. I don’t suffer from bad spots or acne but sometimes have a few that appear in the same area that I treat. I can’t decide whether to stick with outsmart blemish treatment or try this- what are the main differences/benefits of both?
Hi Lynsey L, This is a new type of technology that targets the bad bacteria that causes breakouts and gently unclogs pores with a blend of salicylic acid and mandelic acid, that also helps even skin tone and reduces post inflammatory hyperpigmentation that is often a concern after the break outs have diminished. The idea is to treat and prevent breakouts with these ingredients that help to keep the skins microbiome in the most healthy condition.
Where does an exfoliant fit into a routine that includes this serum? Or won't I need an exfoliant any more?
Hi Clare, You could use an exfoliant 2-3 times a week. We would recommend our AHA/ BHA Exfoliating Cleanser used in the morning 2-3 times a week as a gentle exfoliating product, or Renewing Cleanser which contains peptides and lactic acid to gently cleanse and exfoliate, if you do not want to use a manual exfoliator. Always go on your skin's own comfort level.
Is the serum gentle enough for mature skin?
Hi Aly P, Yes this serum is ideal for all skin types regardless of age. The treatment is to balance the microbiome and to reduce the communication of bad bacteria to prevent over population of the bacteria that contributes to breakouts, while being super gentle on skin. It is also ideal for people that have breakouts all the time and all over the face.
Does it have a fragrance?
Hi Janet, This product has no fragrance, artificial colour or alcohol. Hope that helps!

Frequently Asked Questions

    This transformative serum contains 1.0% Salicylic Acid, to clear and prevent blemishes while penetrating deeply under the skin surface and decongest clogged pores; Biome-Sensitive Technology, to stimulate healthier and more balanced microbiome to prevent blemishes' recurrence; Mandelic Acid, to smooth and even complexion and Glutamic Acid, to stimulate the natural production of GABA, a protective amino acid for healthier-looking, smoother skin.

    Blemish-prone skin and those with mild-to-moderate breakouts, plus anyone wanting a healthier, more balanced microbiome that's naturally more resistant to recurring blemishes.

    Apply 1-2 pumps of Biome-Balancing Clear & Prevent Blemish Treatment Serum to face and neck, after Clarifying Cleanser or Clarifying Cream Cleanser; let dry completely before applying moisturiser and Superactive Mattifying Oil + Pore Control SPF 40 during the day, before makeup. Can be used in conjunction with Deep Relief Blemish Treatment at night, to treat spots.

    It's formulated to be non-drying and non-irritating and many users find it gentle, but individual reactions can vary. 92% agreed it hadn't caused unwanted side effects like irritation, peeling, flaking, or redness.

    Gel-serum: lightweight, slightly tacky on application, absorbs quickly. Minimal to no scent; some users note a faint floral note.

    Yes. The formula layers well under makeup for most users and is reported to avoid pilling.

    The formula contains 1.0% salicylic acid to help clear skin in as little as 3 days. It reduces active breakouts, improves skin clarity, and helps minimise the recurrence of blemishes.

    Clinical testing was performed on those with mild-moderate blemishes. For deep, painful bumps and blemishes, we recommend Deep Relief Blemish Treatment.

    This breakthrough serum targets all types of breakouts, from whiteheads to hormonal blemishes, with visible results in as little as 3 days. Powered by pioneering Biome-Balancing Technology, it works in sync with your skin's unique microbiome to help clear blemishes, prevent future breakouts, and support the skin's natural production of proactive amino acids for healthier-looking skin. Enriched with salicylic acid to decongest clogged pores and Mandelic acid to smooth and even skin tone, it helps reduce active breakouts while improving skin clarity and making skin more resilient against recurring blemishes.

    Apply 1-2 pumps of Biome-Balancing Clear & Prevent Blemish Treatment Serum to face and neck, after Clarifying Cleanser or Clarifying Cream Cleanser; let dry completely before applying moisturiser and Superactive Mattifying Oil + Pore Control SPF 40 during the day, before makeup. Can be used in conjunction with Deep Relief Blemish Treatment at night, to treat spots.

    Yes, but do not layer. Rather, use Biome-Balancing Blemish Treatment Serum in the morning and Deep Relief Blemish Treatment at night.

    The serum works for balanced, oily, and combination skin types.

    This serum is clinically proven to help clear the skin in just 3 days and to reduce active breakouts, improving skin health and clarity while reducing risk of recurrence.

    Yes, it's non-irritating, non-drying, and gentle enough for daily use, with clinical results showing no redness, peeling, flaking, or irritation in testing.

    Unlike typical treatments, it not only clears breakouts with proven actives but also uses Biome-Sensing Tech and glutamic acid to empower the microbiome against future breakouts for long-term smoother, clearer skin.

    Yes, it's gentle enough for daily use, non-comedogenic, non-drying, and layers well under makeup without pilling or flaking.

    Yes, this serum is designed to clear all types of breakouts, including hormonal ones.

    It's formulated without parabens, sulphates, phthalates, gluten, and animal-derived ingredients.